Nineteen of the Russian's 21 championships have been earned on hard surfaces
A resurgent the Russian player won his initial championship for 882 days with a win over Corentin Moutet in the competition championship match.
The athlete, a ex- world number one, has experienced a challenging period, winning just one win at the major tournaments and undergoing a setback at the US Open.
His varied form on the tennis tour - and difficulties with his serving in specific - resulted in him dropping out of the elite rankings and ultimately parting ways with former coach Cervara.
Now training with his coach and Goetzke, Medvedev has gradually advanced in the last few weeks - peaking in a closely contested three-set win over opponent Moutet.
This represents the player's maiden championship after the Rome competition and initial on a hard surface since spring of that year.
The win also signifies he has secured 21 championships at twenty-one different tournaments.
"This marks the first occasion I am participating in a event with my two daughters at once, so to win a title is really nice," said world number 14 Daniil Medvedev.
"This championship is in dedication of my child her name, because the maiden victory I won when my first daughter Alisa was born was for her."
Medvedev, the former major winner, had failed in his previous six championship matches, comprising in Halle earlier this year.
Medvedev's defensive approach and frequent outbursts on the tennis court had prompted some to wonder if his ability to perform at the top level was concluded.
However the player has implemented adjustments in the past month, attempting to advance forward and perform positively, backed up by an improved serve.
He fought back from a deficit in the initial set against the difficult Moutet, securing 4 of the concluding five points to take the lead.
The pair exchanged service breaks in the second set before Moutet, attempting for his maiden professional championship, gained dominance to push for a decider.
The opponent rescued 4 early-game chances in a close deciding set before Medvedev secured a break to that score to serve for the match.
Fittingly, the winner clinched the win with a point at the net, with Moutet unable to control a volley after over two and a half hours.